Arq. Bras. Oftalmol. 2026; 89 (4): 10.5935/0004-2749.2025-0225
Total: 24
Plínio Augusto Trindade Abreu1; Juan Silva Locks Camargo2; Lais Bomediano de Souza3; José Paulo Cabral de Vasconcelos1, Osias Francisco de Souza1
DOI: 10.5935/0004-2749.2025-0225
ABSTRACT
PURPOSE: To compare the impact of pro re nata and treat-and-extend regimens on quality of life in patients with neovascular age-related macular degeneration.
METHODS: This cross-sectional study included 81 patients with neovascular age-related macular degeneration who completed the National Eye Institute Visual Function Questionnaire-25.
RESULTS: No statistically significant differences were observed between pro re nata and treat-and-extend regimens across quality-of-life domains measured by National Eye Institute Visual Function Questionnaire-25.
CONCLUSIONS: Pro re nata and treat-and-extend regimens demonstrated comparable effects on quality of life in patients with neovascular age-related macular degeneration. Further studies are warranted to determine optimal standardized treatment strategies.
Keywords: Macular degeneration/diagnosis; Fluorescein angiography/methods; Tomography, optical coherence/methods; Macular degeneration/drug therapy; Drug administration schedule; Angiogenesis inhibitors/therapeutic use; Intravitreal Injections; Surveys and question
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