Dear Editor,

We would like to share our viewpoints on the article entitled “Multiple evanescent white dot syndrome (MEWDS) following inactivated COVID-19 vaccination (Sinovac-CoronaVac)⁽¹⁾” by Tomishige et al.⁽¹⁾ The authors presented a relevant case and discussed about the interplay of COVID-19 immunization and the case. We agree, based on the accumulated recorded data from post-vaccination adverse effect surveillance system, that the COVID-19 vaccination can result in a variety of clinical issues, including eye disorders. The current case may or may not, however, be related to the COVID-19 vaccination. For instance, there is no information about the patient’s immunological or ocular condition prior to vaccination. Conclusions about any interaction are therefore difficult to reach. It is important to keep in mind that the recurrence could be caused by a past medical condition or a concurrent medical disorder. After vaccination, for example, the vaccine recipient may get an arbovirus infection⁽²⁾. The present case could hence be that of a rare but probable cause of MEWDS from arbovirus infection⁽³⁾.

REFERENCES

1. Tomishige KS, Novais EA, Finamor LP, Nascimento HM, Belfort Jr. R. Multiple evanescent white dot syndrome (MEWDS) following inactivated COVID-19 vaccination (Sinovac-CoronaVac). Arq Bras Oftalmol. 2022 Jan 21:S0004-27492022005001201. ahead of print.

2. Kebayoon A, Wiwanitkit V. Dengue after COVID-19 vaccination: possible and might be missed. Clin Appl Thromb Hemost[Internet]. 2021[cited 2022 Apr 5];27:10760296211047229.Available from: Dengue After COVID-19 Vaccination: Possible and Might be Missed - PMC (nih.gov)

3. Ju R, Zhang J, Zhang J, WuB, Deng Y. Ophthalmic complications related to dengue fever: a case report. Yan Ke Xue Bao. 2016;31(3): 178-81.

Submitted for publication: March 21, 2022.
Accepted for publication: March 23, 2022.

Funding: This study received no specific financial support.

Disclosure of potential conflicts of interest: None of the authors have any potential conflicts of interest to disclose.