Choroiditis following severe acute respiratory syndrome coronavirus 2 infection in unvaccinated identical twins

Mello, Luiz Guilherme Marchesi; Lubiana, Lara Guedes; Hirata, Carlos Eduardo; Monteiro, Mário Luiz Ribeiro; Yamamoto, Joyce Hisae

doi:10.5935/0004-2749.2023-0117

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Choroiditis following severe acute respiratory syndrome coronavirus 2 infection in unvaccinated identical twins

Luiz Guilherme Marchesi Mello^1,2,3; Lara Guedes Lubiana²; Carlos Eduardo Hirata¹; Mário Luiz Ribeiro Monteiro¹; Joyce Hisae Yamamoto¹

DOI: 10.5935/0004-2749.2023-0117

ABSTRACT

Unvaccinated identical twins developed bilateral anterior uveitis soon after the onset of coronavirus disease 2019 symptoms. During follow-up, both patients developed choroiditis, and one twine developed posterior scleritis and serous retinal detachment. Prompt treatment with oral prednisone ameliorated the lesions, and no recurrence was observed at the 18-month follow-up. Choroiditis may rarely be associated with severe acute respiratory syndrome coronavirus 2 infection, and it responds well to corticosteroid therapy. Although the exact mechanism is unknown, we hypothesize that the virus may act as an immunological trigger for choroiditis.

Keywords: Choroiditis; Coronavirus; COVID-19; SARS-CoV-2; Uveitis